At 48 h and 72h p.i., AcMNPV-WIV-Syn1-infected cells showed typical phenomena of late-stage infection, where occlusion bodies with multi-nucleocapsid ODVs accumulated at the ring zone of the nucleus, while AcMNPV-Syn-mC1-1.1 showed enlarged nuclei and nucleocapsids assembled around the ring zone. The gene discussed is ATP7A; the disease is infection.