In COVID-19 samples, there was a significant decrease in the following genes compared with healthy subjects: 0.985-fold for PROS1, 1.108-fold for S1PR1, 1.323-fold for THBD, 0.502-fold for PROC, 0.767-fold for RAC1, 0.841-fold for RHOA, and 0.207-fold for TP53 (p < 0.05) (Table 1; Figure 4B). Here, S1PR1 is linked to COVID-19.