PSMD1 and infection: Earlier research suggested that pAPN is the functional host receptor of PEDV, based evidence that anti-pAPN antibody disrupted the interaction between PEDV and pAPN in swine testis (ST) and intestinal cells, overexpression of exogenous pAPN increased PEDV infection in ST cells, and the PEDV S1 subunit binds effectively to pAPN by dot blot hybridization [46,47].