The presence of elevated levels of MDC and TARC in the lungs of RSV convalescent mice post-challenge suggests that even recovery from natural RSV infection may not completely prevent priming for undesirable immune responses upon subsequent infection, while a focused immunization with G CX3C concomitant with engagement of the innate immune system (Pam3.GM2) does effectively prevent post-infection inflammatory responses in the lung while also protecting the host from RSV infection. Here, CCL17 is linked to infection.