A binary logistic regression analysis using the total serum IgE, the presence of comorbidities (RS, ACO, and GERD), EOS count, whether the serum IgE was positive, and FEV1 and PEF as correlates yielded an R2 = 0.242; the OR, 95CI, and p-values are shown in the Cox forest plot (Figure 2). The gene discussed is IGHE; the disease is gastroesophageal reflux disease.