TMPRSS2 and COVID-19: In order to evaluate the efficacy of MGF on the expression of the main factors that contribute to the virulence of SARS-CoV-2 and pathogenesis of coronavirus disease-19 (COVID-19), angiotensin-converting enzyme 2 (ACE2), and trans-membrane protease serine 2 (TMPRSS2), changes in their mRNA levels were measured following the treatments (Figure 3).