As listed in Table 1, AF in combination with vitamin C, anti-PD-L1, MK2206, adriamycin, cisplatin, buthionine sulfoximine, cold atmospheric plasma etc. showed statistically significant reduction in tumor growth and/or prolonged survival, without obvious side effects, in several in vivo cancer models [25,26,33,35,37,40,41,45]. This evidence concerns the gene CD274 and cancer.