An Artemisia vulgaris EO NE exhibited remarkable cell-selective cytotoxic, apoptotic, and antioxidant activities against MCF-7 cancer cells via upregulating caspase-9, CAT, and SOD gene expression, restrained angiogenesis in MCF-7 breast cancer cells via down-regulating VEGF gene expression, and reduced the number and length of chick CAM blood vessels, suggesting its anti-angiogenic activity [135]. This evidence concerns the gene VEGFA and cancer.