FOXA1 and breast carcinoma: Forkhead box transcription factor (FOXA1) was used as a therapeutic target in the application of CCMV delivery of siRNA, and cell penetrating peptides (CPPs), L17E, were covalently coupled to the surface of CCMV loaded with siRNA, effectively silencing FOXA1, the target gene of mcf-7 in breast cancer cells [56].