As for macrophages, liposomes coated with RAW264.7 membranes have been shown to specifically mediate and increase the uptake of NPs in breast cancer through the interaction of integrin α4β1, which is present on the macrophages membrane, and vascular-cell adhesion molecule 1 (VCAM-1), which is expressed by cancer cells. This evidence concerns the gene VCAM1 and breast cancer.