These favorable properties of ILQ-SNEDDS improve the bioavailability of ILQ and made ILQ show excellent anti-EoE activity by inhibiting the production of TH2-inflammatory cytokines and PPE-s-IgE, and the expression of TGF-β1 in EoE model mice. This evidence concerns the gene TGFB1 and eosinophilic esophagitis.