INS and diabetes mellitus: Insulin users were older (56.7± 13.1 vs. 50.6 ± 12.9 years; p < 0.001), had longer diabetes duration (12.1 ± 7.1 vs. 8.7 ± 6.5 years; p < 0.001), and had higher HbA1C (9.50 ± 1.70 vs. 8.84 ± 1.60 %; p < 0.001), whereas body mass index (BMI) was lower (29.4 ± 5.2 vs. 31.3 ± 5.3; p = 0.001).