ACHE and amnesia: It also showed good self and AChE-induced Aβ aggregation inhibition at 10 μM in thioflavin T assay (self-induced = 30.85%; AChE-induced = 50.64%) in comparison to donepezil (self-induced = 21.24%; AChE-induced = 33.22%) In in vivo studies, the compound exhibited a remarkable improvement in cognitive dysfunction at 10 mg/kg in scopolamine-induced amnesia mouse models [188].