In addition, EGCG could upregulate the mRNA and protein levels of NRF2, uridine 5′-diphosphate-glucuronosyltransferase (UGT)1A, and UGT1A8, followed by the suppression of proliferation and liver and lung metastasis in an HT-29 cancer cell mouse model [126]. The gene discussed is NFE2L2; the disease is cancer.