Recent studies have shown that resveratrol induces the elevation of intracellular ROS by attenuating SOD2 and CAT expression and promoting the activity of caspase-9 and caspase-3, thereby remarkably arresting proliferation and triggering extensive apoptosis in glioblastoma multiforme (GBM) cells [164]. The gene discussed is SOD2; the disease is glioblastoma.