To evaluate antitumor efficacy, a pilot experiment was conducted using 5 groups of 22Rv1 tumor-bearing nude mice, injected with 74 MBq of [177Lu]Lu-PSMA-BP, [177Lu]Lu-PSMA-4PY, [177Lu]Lu-PSMA-Q, [177Lu]Lu-PSMA-617 or saline (n = 10/group). The gene discussed is FOLH1; the disease is neoplasm.