CXCL8 and lung carcinoma: UA suppressed IL-8 production in LPS-stimulated lung cancer (A549) cells with an IC50 value of 2.0 ± 0.14 μM, while OA inhibited IL-8 production at a concentration > 125 μM, which was also toxic to the cells, suggesting that the inhibition of IL-8 was related to the antiproliferative activity [52].