TGFB1 and renal fibrosis: Numerous studies have revealed the mediators of kidney fibrosis, including transforming growth factor-β1 (TGF-β1), connective tissue growth factor, and CC motif chemokine 2; and TGF-β1 has been established as the ‘master regulator’ that plays a pivotal role in renal fibrosis and subsequent kidney function deterioration [11,12,13,14].