In seven primary HCMV infections in D+R− kidney transplant patients we measured IFNγ responses from as early as 4 weeks after infection to mixes of HCMV proteins containing IE1 and IE2, latency-associated proteins (UL138, US28, LUNA and vIL-10), pp71 and US3. This evidence concerns the gene IFNG and cytomegalovirus infection.