To clarify the expression pattern of the grapevine SAPs gene family under biotic stress, in this study, the expression levels of the grapevine SAP family in native American grapevines (V. rupestris expressing GFP-AtTUB6), native European grapevine (V. vinifera ‘Cabernet Sauvignon’) and a hybrid species (V. aestivalis × V. vinifera ‘Norton’) challenged by fungi infection were compared (Figure 6) [30,33]. The gene discussed is SKAP2; the disease is fungal infectious disease.