NFE2L2 and liver dysplastic nodule: Ma et al. have shown that baicalin, a bioactive flavonoid from the root of the medicinal plant Scutellaria baicalensis, can treat DN by alleviating oxidative stress and inflammation by the activation of the Nrf2-mediated antioxidant signaling pathway, and the inhibition of the MAPK-mediated inflammatory signaling pathway [105].