To date, the list of Hsp70 inducers includes celastrol, arimoclomol [40], geranylgeranyl-acetone [41], and U-133 [42]; the compounds have undergone pre-clinical trials, and as far as we know, the latter has been subjected to clinical trials as the medicine for orphan lysosome storage disease [43]. This evidence concerns the gene HSPA1A and lysosomal storage disease.