The pathways relevant to cancer pathogenesis were proteoglycans in cancer, prostate cancer, prolactin signaling, PI3K-AKT signaling, pathway in cancer, pancreatic cancer, microRNA in cancer, growth hormone, FoxO signaling, focal adhesion, ErbB signaling, EGFR tyrosine kinase inhibitor resistance, colorectal cancer, autophagy, T-cell receptor signaling, sphingolipid signaling, and apoptosis. This evidence concerns the gene PIK3CA and prostate cancer.