Within a few hours of infection, the recognition of viral components called pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs) in the alveolar cells and site of invasion, such as Toll-like receptors and retinoic acid-inducible gene-1 (RIG-1)-like receptors, activate the innate immune response [11]. This evidence concerns the gene PLAAT4 and infection.