NOS3 and myocardial infarction: Hydroxysafflor yellow A (HSYA), the main component of safflower, had a myocardial protective effect through reducing the area of myocardial infarction, increasing the activity of SOD, reducing the content of MDA, inhibiting the activity of endothelial nitric oxide synthase, and reducing the levels of NO and creatine kinase isoenzyme [14,15].