By correlating 96 plasma proteins with left ventricular ejection fraction measured at 4 months post-MI, researchers illustrated six top proteins potentially coregulated in post-MI heart failure: N-terminal B-type natriuretic peptide (NT-BNP) and troponin T (TNNT2), and newly emergent biomarkers, angiopoietin-2 (ANGPT2), thrombospondin-2 (THBS2), latent transforming growth factor-β binding protein-4 (LTBP4), and follistatin-related protein-3 (FSTL3), as well [72]. This evidence concerns the gene THBS2 and heart failure.