IL6 and rheumatoid arthritis: The results demonstrated that sinomenine can regulate eotaxin-2, GM-CSF, IL-1α, IL-1β, IL-6, IL-10, IL-12 p40, KC (CXCL1), MCP-1, M-CSF, RANTES, and TNF-α secretion and reduce RA activity and the DAS28 score.