Another study supported this idea by demonstrating how the F. prausnitzii-derived microbial anti-inflammatory molecule (MAM), a bioactive peptide produced by F. prausnitzii and derived from a single 15 kDa protein (ZP05614546.1), suppressed the NF-κB pathway utilizing the NF-κB-luciferase in vivo in a mice model of induced colitis [41]. This evidence concerns the gene NFKB1 and colitis.