Enterobactin (EntF, FepC, FepG, EntD, EntE, FepB, FepD, Fes, EntS), which was highly detected in advanced-stage CRC stool, has been previously studied and shown to play a role in promoting a pro-inflammatory response, as well as reducing basal reactive oxygen species (ROS) generation in Intestinal epithelial cells [35]. Here, FES is linked to colorectal carcinoma.