It is apparent from Figure 5 that, regarding the cytokine profile, we found significant upregulations in IFN-α2, IL-10, IL-18, IFN-γ and IL-6 in the sera of COVID-19 patients when compared with samples of patients who were hospitalized during their COVID-19 disease course (at some point before or after sample obtainment). This evidence concerns the gene IL18 and COVID-19.