Oleoyl lysophosphatidylcholine (LPC 18:1) binds to the membrane receptor of GPR119 on β-cells, regulating insulin secretion through a protein kinase A (PKA)-related signaling pathway [31,32], and promotes glucose-stimulated insulin secretion in murine NIT-1 insulinoma cells [30,31]. The gene discussed is INS; the disease is pancreatic insulinoma.