CEACAM5 and neoplasm: Then, univariate Cox regression analysis revealed that high NMPR (p = 0.001), tumor length (p = 0.002), vessel invasion (p = 0.004), poor tumor differentiation (p = 0.023), advanced T stage (p < 0.001), advanced N stage (p < 0.001), high CEA (p = 0.009) and high CRP (p < 0.001) were significantly associated with poor OS (Table 2).