Mechanically, the neutrophil population increased under inflammatory conditions, such as in a tumor-bearing body, secreting a large amount of nitric oxide, arginase, cytokines and reactive oxygen species, resulting in disorders of T cell activation and stimulating the production of vascular endothelial growth factor (VEGF) to accelerate tumor neovascularization [24,25,26]. The gene discussed is VEGFA; the disease is neoplasm.