MUC1 and interstitial lung disease: According to the paper by Shiraishi K et al., digital clubbing has been associated with high serum Krebs von den Lugen (KL-6) levels and decreased pulmonary function; however, it has been found with heterogeneous frequency in ILDs, with percentage values of 20.8% in non-CTD-ILD cases, 12% in CTD-ILD patterns, and 25% in ILD related to Scleroderma.