However, whether these foodborne PVL-positive strains, which are negative for toxin genes (sea, seb, sec, sed, see, eta, etb, and tst genes) [26], can cause a severe infection such as potential necrotising pneumonia in humans and animals, is a crucial issue concerning public health and requires a thorough investigation by in vivo studies. Here, SETBP1 is linked to susceptibility to pneumonia measurement.