ACE and endocrine system disorder: Genetic factors are various [1,2,3], and other factors that may trigger or exacerbate psoriasis can include: stress, body mass index (BMI), infection, drugs (beta-blockers, lithium, angiotensin-converting enzyme (ACE)-inhibitors, (synthetic) antimalarials, tetracyclines, non-steroidal anti-inflammatory drugs (NSAIDs)), withdrawal of systemic (or even potent local) corticosteroids, chronic alcohol consumption, smoking, friction, minimal trauma of the skin—even a slight irritation, radiotherapy, endocrine disorders, and many other [3,4,5,6].