TGFB1 and schizophrenia: Frydecka et al. [53] have shown that the TGFB1 +869T/C gene polymorphism is associated with schizophrenia, especially among females; no differences were found in the severity of schizophrenia symptoms registered by PANSS between males and females with schizophrenia, suggesting that sex is a potentially important factor for group differences in cytokine levels.