BACH2 and cancer: One study reported that miR-148a-3p regulates the Ras/MAPK/Erk signaling pathway to suppress cancer by targeting Son of sevenless 2 (one of the guanylate nucleotide exchange factors) [94] and ultimately affects B cell differentiation by targeting transcription factor mRNAs, such as Bach2, Mitf, and others [95,96].