EGFR and non-small cell lung carcinoma: As for lung tumors, Zheng et al. demonstrated that concurrent EGFR-TKI and radiotherapy within 2 weeks of targeted therapy as the first-line treatment for advanced NSCLC harboring the EGFR mutation showed a long-term control of primary lung lesion and acceptable serious AEs, with 13.0 months of PFS and a 57.1% 1-year PFS rate [20].