Logistic regression analysis of these variables and clinical characteristics (including age, gender, tumor node metastasis (TNM), tumor stage, and prior malignancies) revealed that only distant metastasis, lymph node metastasis, CACNA2D1, and PRLR registered a significant correlation with the prognosis of BC. Here, CACNA2D1 is linked to metastatic malignant neoplasm in the lymph nodes.