We used TIMER to evaluate the effect of immune cell infiltration on the clinical prognosis of BC patients, and found that lower levels of B cells, CD8+ T cells, CD4+ T cells, neutrophils, and dendritic cells were related to a worse prognosis of BC patients, while the expression of macrophages was not significantly correlated to the prognosis of BC (Figure 11A). This evidence concerns the gene CD4 and breast cancer.