PRLR and breast cancer: Yuexian Zhou et al., proposed that T-cell-mediated cytotoxicity was related to PRLR expression [42] and Tomohiro Yonezawa et al. showed that knocking down long PRLR might inhibit distant metastasis by modifying the tumor microenvironment, and the type of immune infiltrating cells in liver metastasis in the homologous model of 4T1 mouse BC cell line experienced changes [43].