PMEL and melanoma: Recent studies have shown that melanoma antigens (e.g., gp100/MART-1), encapsulated in palmitoylated synthetic long peptides and alpha-galactosylceramide liposomes containing LeY, were better up-taken by monocyte-derived DCs, DCs and LCs, hence promoting a better activation of gp100-specific CD8+ T- and iNKT cells [81,82].