ORAI1 and cancer: Enhancement of endoplasmic reticulum (ER) transmembrane stromal interaction molecule 1 (STIM1) and/or Calcium Release-Activated Calcium Modulator 1 (Orai1) expression in Huh-7 CSCs increased store-operated Ca2+ entry (SOCE) and proliferation rate along with upregulated MDR1 expression, each associated with poor cancer prognosis [7].