The genes PCDHA7, CD93, SGSM1, TRPC7, ADAMTSL4, TAOK1, TADA2B, PABPC3, ATP8B1, ADAM22, POU5F2, P3H1, KCNV2, FAM193A, MOCOS, UBA6, KIAA1683, CDH16, DHX35, SMC3, RBM22, IFFO, KIAA0556, TBPL2, DIAPH1, LPCAT3, ELP3, ZFP57, EEF1D, GABBR2, NR0B2, ATN1, HPR, ECT2L, CYP2U1, and ITPRID2 have not previously been associated with GC and are therefore a novel array of putative GC markers and/or therapeutic targets whose mutation could enhance CDH1 expression. This evidence concerns the gene SMC3 and gastric cancer.