On the other hand, HLA-DRB1*0101 (p = 0.022, OR = 0.20), HLA-DRB1*0403 (p = 0.023, OR = 0.04), HLA-DRB1*0701 (p = 0.004, OR = 0.35), HLA-DRB1*1301 (p = 0.016, OR = 0.27) and DRB1*1401 (p = 0.042, OR = 0.05) were negatively linked to SLE. This evidence concerns the gene HLA-DRB1 and systemic lupus erythematosus.