Genes co-expressed with PTPN6 were correlated with “Immune response_T cell co-signaling receptors, schema”, “Breakdown of CD4+ T cell peripheral tolerance in type 1 diabetes mellitus”, and “Chemotaxis_SDF-1/CXCR4-induced chemotaxis of immune cells” (Figure 9, Supplementary Table S6). Here, CXCR4 is linked to diabetes mellitus.