According to various database analyses, PTPN3, PTPN7, PTPN12, and PTPN14 were expressed at higher levels, while expressions of PTPN1, PTPN5, PTPN6, PTPN9, PTPN12, PTPN13, PTPN18, PTPN21, and PTPN22 were downregulated in lung cancer. The gene discussed is PTPN21; the disease is lung carcinoma.