In clinical practice, the main challenge is identifying LV-GCA in patients with PMR, given that clinical signs of LV-GCA are less specific because they are often limited to constitutional symptoms (asthenia, anorexia, weight loss, unexplained fever) with an increase in acute phase reactants (erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP)). Here, CRP is linked to temporal arteritis.