DUOX2 was the most common CH-causing gene (15/33, 45.5%), followed by TG (2/33, 6.1%), TPO (2/33, 6.1%), DUOXA2 (2/33, 6.1%) and PAX8 (1/33, 3.0%). The gene discussed is DUOX2; the disease is cyclic hematopoiesis.