Our data are in line with the recently published results [7,40,41,42,43,44,45,46]: we found that APTT, thrombin time, fibrinogen and D-dimer levels, but not INR or prothrombin time, are significantly higher in “severe” patients with more than 25% lung involvement as compared to “mild” COVID-19 patients (Table 1). Here, F2 is linked to COVID-19.