Since PLAUR rs2302524 was identified as the SNP, significantly associated with the lung damage severity, the serum level of uPAR protein was also tested, and it was significantly higher in the “severe” COVID-19 group (p < 0.0001, t-test, Table 1), indicating that uPAR may serve as a good indicator of the disease severity. This evidence concerns the gene PLAUR and COVID-19.