Cannabichromene (CBC), a phytocannabinoid frequently detected in artisanal cannabis oils, and other CBC-related derivatives (5-fluoro-CBC, cannabichromenic acid CBCA, cannabichromevarinic acid CBCVA) have recently shown anti-seizure effects against hyperthermia-induced seizures in Scn1a+/− mouse model of DS [149]. The gene discussed is SCN1A; the disease is Dravet syndrome.