In the other circumstance, Ling et al. [36] proved in their observational study that neuroinflammation is a phenomenon characteristic of psychiatric disorders, as strengthened by the level of IL-1β, which was significantly upregulated and antithetical to that of interferon-gamma (IFN-γ), presumably because of the β-diversity following the linear discriminant analysis effect size (LEfSe). This evidence concerns the gene IL1B and psychiatric disorder.