It is well-known that infection with exogenous viruses, such as HIV, hepatitis B virus (HBV), Epstein–Barr virus (EBV), Influenza A, Karposi’s sarcoma herpes virus (KSHV), and SARS-CoV-2, can induce significant HERV transactivation concomitant with elevated HERV element expression levels, including the env protein [92,93,94,95,96,97,102,112]. Here, ERVW-1 is linked to infection.