In support of the benefit roles of Blnc1 in adipose, a study from another team showed that overexpression of Blnc1 in eWAT by multi-point injection of adenovirus carrying Blnc1 into eWAT on both sides of HFD-induced obese mice ameliorated glucose intolerance, hepatic steatosis and systemic IR and attenuated mitochondrial dysfunction as evidenced by increased mitochondrial mass and expression of genes related to mitochondrial functions. Here, PAQR9 is linked to Glucose intolerance.